![]() ![]() Results demonstrated that participants increased their total strength on the bench press, squat, and deadlift by 121.9 pounds. The University of Tampa conducted a 12-week clinical study to determine the effectiveness of Peak ATP. Lastly, it’s thought that optiNOs promotes ATP in skeletal muscle cells, creating more energy that’s used by hardworking muscles. This also involves enhanced myogenesis through the increased production of muscle-specific transcription factors like myogenin, Myf-6. New research suggests that optiNOs also initiates mTOR signaling with signaling factor p70S6K in skeletal muscle cells. More nutrients and oxygen get delivered to the muscles while the body rids itself of metabolic waste. One of the mechanisms includes an elevated nitric oxide production in endothelial cells by activating Nitric Oxide synthase (eNOs). OptiNOs is a patent blend of three ingredients - Cissus, Curcuma, and Ajowan Extract - each working via multiple mechanisms. This key ingredient also supports vasodilation for a better blood flow, which delivers more oxygen and nutrients to your muscles. Peak ATP increases anabolic signaling while reducing skeletal muscle calcium influx and release - leading to an improved muscle contraction. ![]() The last of the “Trilogy” stack is Plasma Muscle, another mTOR activating supp through two leading ingredients - Peak ATP and optiNOs. It provides the most extreme muscle-building pumps you’ve ever experienced along with lean muscle gains! These participants also increased their strength on the leg press by 60 percent.įeaturing a never-before-seen combination of Peak ATP and optiNOs, Plasma Muscle is a serious musclebuilder for hardcore athletes looking for only the most cutting-edge performance enhancement and muscle growth. Nutrition & Metabolism proved that soy-derived phosphatidic acid increased mTOR the most.Īt the University of Tampa, participants supplementing with Mediator packed on 5.3 pounds of muscle in eight weeks. Pre-clinical research has shown that phosphatidic acid enhanced mTOR signaling by over six times compared to baseline. The more phosphaticdic acid that’s present, the more amplified effect it has on protein synthesis. From there, the lipid binds to mTOR and activates mTOR complex 1, which causes the growth and repair of muscle. For starters, when you lift a heavy load, your muscle fibers receive that mechanical stimulus - triggering the release of phosphatidic acid. Phospha Muscle powers the mTOR pathway through phosphaticdic acid (Mediator ingredient), which is a signaling lipid. PHOSPHA MUSCLE delivers the purest form of phosphatidic acid to boost these effects and give you the size and strength you want! Also participants had an overall increased strength by over 170 pounds from the initial testing. The European Journal of Applied Physiology published the results: participants who supplemented with BetaTOR gained 16.3 pounds of muscle in 12 weeks. The study encompassed eight weeks (phase 1) of nonlinear periodized resistance-training, two weeks (phase 2) of an overreaching cycle, and two weeks (phase 3) of a taper. The Journal of Physiology published a study in 2013 indicating the ingredient, BetaTOR, can reduce protein breakdown by 57 percent.īetaTOR was put the test at the University of Tampa, where a group of participants were given the ingredient. By inhibiting this pathway, Clear Muscle decreases the muscle protein breakdown at a molecular level, caused from an intense training session. The supp also works by shutting down the activity of the ubiquitin-proteosome-proteolytic pathway (UPP). BetaTOR increases the phosphorylation of the pathway. Its main function is stimulating the mTOR pathway for greater protein synthesis with the ingredient BetaTOR. The CLEAR MUSCLE formula is the first to contain BetaTOR, and is only available from MuscleTech in a clear liquid pill.Ĭlear Muscle increases anabolic protein synthesis while inhibiting muscle catabolism. ![]()
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